Easter News: Covid Killing Secret Exposed

There is a breakthrough in understanding how Covid19 kills people. How fitting that such good news arrives on Easter Sunday. A great H/T to Ice Age Now for breaking this story along with others.

Caroline Snyder writes Covid-19 had us all fooled, but we might have found its secret. Excerpts in italics with my bolds.

Why chloroquine and Z-Pak (also known as azithromycin or Zithromax) work.

I have been thinking this for several weeks now, so it is good to see other folks thinking the same. By the way, I am an RN and a Nutritional Biochemist in former times.

The Malaria-COVID-19 connection is explained very well here in this link (text reprinted at end)

I am unpacking this to a very simple level so all of you can understand why Z-Pak, also known as azithromycin or Zithromax, works, as does the Quinine derivative chloroquine! That doctor compares the presentation to that of altitude sickness, and he is spot-on! (See “We are treating the wrong disease.”)

Like Malaria, the coronavirus “ROBS” red blood cells of the ability to “collect and transfer” oxygen to wherever it is needed. This results in lower and lower Oxygen levels.. organs start to fail as they can’t get enough oxygen to function properly.. people die…. this alone is likely why those who already have eg Kidney or Heart, or Liver Failure, have a high morbidity.. also anyone who doesn’t have a SPLEEN is at VERY high risk as the spleen is involved with filtering your blood. The spleen affects the number of red blood cells that carry oxygen throughout your body, by breaking down and removing cells that are abnormal, old, or damaged.. also If you have COPD, or are a smoker, and/or have Cardiovascular Disease, you ALREADY have impaired Oxygen transport mechanisms, so this is another perfectly logical co-morbidity!

In this article, the Red Blood Cells (RBCs) are compared to truck cabs running around furiously with no payload (OXYGEN).. so simply pumping oxygen into the lungs under pressure will NOT work, unless you address the “diseased “Red Blood Cells, which are the OXYGEN CARRIERS. which both Quinine derivatives and Z-Pak address, along with (interestingly!) Vitamin C and other “cell-protective” Antioxidants address.

NOW it makes perfect sense.. the biggest clue is that the “pneumonia” is always bilateral with COVID-19, unlike almost every other case of pneumonia which typically affects just ONE lung! 

The body’s response to low Oxygen levels is to make more red blood cells, so that is why high red blood cell levels are also found in the sickest patients.

Covid-19 had us all fooled, but now we might have finally found its secret.

A more detailed explanation from link mentioned in text above:

In the last 3–5 days, a mountain of anecdotal evidence has come out of NYC, Italy, Spain, etc. about COVID-19 and characteristics of patients who get seriously ill. It’s not only piling up but now leading to a general field-level consensus backed up by a few previously little-known studies that we’ve had it all wrong the whole time. Well, a few had some things eerily correct (cough Trump cough), especially with Hydroxychloroquine with Azithromicin, but we’ll get to that in a minute.

There is no ‘pneumonia’ nor ARDS. At least not the ARDS with established treatment protocols and procedures we’re familiar with. Ventilators are not only the wrong solution, but high pressure intubation can actually wind up causing more damage than without, not to mention complications from tracheal scarring and ulcers given the duration of intubation often required… They may still have a use in the immediate future for patients too far to bring back with this newfound knowledge, but moving forward a new treatment protocol needs to be established so we stop treating patients for the wrong disease.

The past 48 hours or so have seen a huge revelation: COVID-19 causes prolonged and progressive hypoxia (starving your body of oxygen) by binding to the heme groups in hemoglobin in your red blood cells. People are simply desaturating (losing o2 in their blood), and that’s what eventually leads to organ failures that kill them, not any form of ARDS or pneumonia. All the damage to the lungs you see in CT scans are from the release of oxidative iron from the hemes, this overwhelms the natural defenses against pulmonary oxidative stress and causes that nice, always-bilateral ground glass opacity in the lungs. Patients returning for re-hospitalization days or weeks after recovery suffering from apparent delayed post-hypoxic leukoencephalopathy strengthen the notion COVID-19 patients are suffering from hypoxia despite no signs of respiratory ‘tire out’ or fatigue.

Here’s the breakdown of the whole process, including some ELI5-level cliff notes. Much has been simplified just to keep it digestible and layman-friendly.

Your red blood cells carry oxygen from your lungs to all your organs and the rest of your body. Red blood cells can do this thanks to hemoglobin, which is a protein consisting of four “hemes”. Hemes have a special kind of iron ion, which is normally quite toxic in its free form, locked away in its center with a porphyrin acting as it’s ‘container’. In this way, the iron ion can be ‘caged’ and carried around safely by the hemoglobin, but used to bind to oxygen when it gets to your lungs.

When the red blood cell gets to the alveoli, or the little sacs in your lungs where all the gas exchange happens, that special little iron ion can flip between FE2+ and FE3+ states with electron exchange and bond to some oxygen, then it goes off on its little merry way to deliver o2 elsewhere.

covid-19-research1

Here’s where COVID-19 comes in. Its glycoproteins bond to the heme, and in doing so that special and toxic oxidative iron ion is “disassociated” (released). It’s basically let out of the cage and now freely roaming around on its own. This is bad for two reasons:

1) Without the iron ion, hemoglobin can no longer bind to oxygen. Once all the hemoglobin is impaired, the red blood cell is essentially turned into a Freightliner truck cab with no trailer and no ability to store its cargo.. it is useless and just running around with COVID-19 virus attached to its porphyrin. All these useless trucks running around not delivering oxygen is what starts to lead to desaturation, or watching the patient’s spo2 levels drop. It is INCORRECT to assume traditional ARDS and in doing so, you’re treating the WRONG DISEASE. Think of it a lot like carbon monoxide poisoning, in which CO is bound to the hemoglobin, making it unable to carry oxygen. In those cases, ventilators aren’t treating the root cause; the patient’s lungs aren’t ‘tiring out’, they’re pumping just fine. The red blood cells just can’t carry o2, end of story. Only in this case, unlike CO poisoning in which eventually the CO can break off, the affected hemoglobin is permanently stripped of its ability to carry o2 because it has lost its iron ion. The body compensates for this lack of o2 carrying capacity and deliveries by having your kidneys release hormones like erythropoietin, which tell your bone marrow factories to ramp up production on new red blood cells with freshly made and fully functioning hemoglobin. This is the reason you find elevated hemoglobin and decreased blood oxygen saturation as one of the 3 primary indicators of whether the shit is about to hit the fan for a particular patient or not.

2) That little iron ion, along with millions of its friends released from other hemes, are now floating through your blood freely. As I mentioned before, this type of iron ion is highly reactive and causes oxidative damage. It turns out that this happens to a limited extent naturally in our bodies and we have cleanup & defense mechanisms to keep the balance. The lungs, in particular, have 3 primary defenses to maintain “iron homeostasis”, 2 of which are in the alveoli, those little sacs in your lungs we talked about earlier. The first of the two are little macrophages that roam around and scavenge up any free radicals like this oxidative iron. The second is a lining on the walls (called the epithelial surface) which has a thin layer of fluid packed with high levels of antioxidant molecules.. things like abscorbic acid (AKA Vitamin C) among others. Well, this is usually good enough for naturally occurring rogue iron ions but with COVID-19 running rampant your body is now basically like a progressive state letting out all the prisoners out of the prisons… it’s just too much iron and it begins to overwhelm your lungs’ countermeasures, and thus begins the process of pulmonary oxidative stress. This leads to damage and inflammation, which leads to all that nasty stuff and damage you see in CT scans of COVID-19 patient lungs.

Ever noticed how it’s always bilateral? (both lungs at the same time) Pneumonia rarely ever does that, but COVID-19 does… EVERY. SINGLE. TIME.

The core point being, treating patients with the iron ions stripped from their hemoglobin (rendering it abnormally nonfunctional) with ventilator intubation is futile, unless you’re just hoping the patient’s immune system will work its magic in time. The root of the illness needs to be addressed.

Best case scenario? Treatment regimen early, before symptoms progress too far. Hydroxychloroquine (more on that in a minute, I promise) with Azithromicin has shown fantastic, albeit critics keep mentioning ‘anecdotal’ to describe the mountain, promise and I’ll explain why it does so well next. But forget straight-up plasma with antibodies, that might work early but if the patient is too far gone they’ll need more. They’ll need all the blood: antibodies and red blood cells. No help in sending over a detachment of ammunition to a soldier already unconscious and bleeding out on the battlefield, you need to send that ammo along with some hemoglobin-stimulant-magic so that he can wake up and fire those shots at the enemy.

The story with Hydroxychloroquine

All that hilariously misguided and counterproductive criticism the media piled on chloroquine (purely for political reasons) as a viable treatment will now go down as the biggest Fake News blunder to rule them all. The media actively engaged their activism to fight ‘bad orange man’ at the cost of thousands of lives. Shame on them.

How does chloroquine work? Same way as it does for malaria. You see, malaria is this little parasite that enters the red blood cells and starts eating hemoglobin as its food source. The reason chloroquine works for malaria is the same reason it works for COVID-19 — while not fully understood, it is suspected to bind to DNA and interfere with the ability to work magic on hemoglobin. The same mechanism that stops malaria from getting its hands on hemoglobin and gobbling it up seems to do the same to COVID-19 (essentially little snippets of DNA in an envelope) from binding to it. On top of that, Hydroxychloroquine (an advanced descendant of regular old chloroquine) lowers the pH which can interfere with the replication of the virus.

Again, while the full details are not known, the entire premise of this potentially ‘game changing’ treatment is to prevent hemoglobin from being interfered with, whether due to malaria or COVID-19.

Update: A more technical discussion and link to published research is here:

Research Reveals That COVID-19 Attacks Hemoglobin In Red Blood Cells, Rendering It Incapable Of Transporting Oxygen.

17 comments

  1. mandclu · April 12, 2020

    “Ice Age Now” is not a reputable information source:
    https://mediabiasfactcheck.com/ice-age-now/

    Like

    • Ron Clutz · April 12, 2020

      That so-called website fact checker is itself biased against any information contrary to IPCC “consensus” alarmism. The list of skeptical blogs extends way beyond Ice Age Now, including WUWT, No Tricks Zone, Climate Etc., CFACT, Friends of Science and so on. All are tarred with denialism, and accused of denigrating the left. How is that for bias?

      Like

      • Elizabeth Whitehouse · April 12, 2020

        Where is the bias in saying that the above mentioned sites are skeptical? They are.

        Like

      • Ron Clutz · April 12, 2020

        Elizabeth, here is what they said. Judge for yourself:

        Overall, we rate NoTricksZone a pseudoscience blog based on the publication of climate change disinformation opposing the consensus of science.

        Overall, they are not Friends of Science and we rate them a Strong Pseudoscience site for the promotion of alternative global warming information.

        Overall, we rate Climate Change Dispatch as a Conspiracy and Quackery level Pseudoscience source for the promotion of false or misleading information that is not inline with the consensus of science.

        Overall, we rate the Climate Depot a strong Pseudoscience source based on promotion of human influenced climate denialism propaganda and the use of poor sources who have failed numerous fact checks.

        Overall, we rate Climate Etc as a pseudoscience website due to its promotion of anti-climate science propaganda.

        Overall, we rate Climatism a strong conspiracy and quackery level pseudoscience website based on the promotion of Agenda 21 conspiracies and human influenced climate change denialism as well as a complete lack of transparency.

        Overall, we rate the Committee for a Constructive Tomorrow (CFACT) a Quackery level Pseudoscience source based on complete rejection of the scientific consensus on climate change as well as the promotion of anti-climate propaganda that is either false or misleading. This is not a credible source for scientific information.

        Overall, we rate Ice Age Now a strong Conspiracy and quackery level Pseudoscience website that is Low in factual reporting through rejection of the consensus of science as well as the publication of false climate news stories.

        Overall, we rate the ICSC a Quackery level pseudoscience organization based on routinely denying human impact on climate change, which differs from the consensus of climate scientists.

        Overall, Iowa Climate Science Education is a quackery level pseudoscience website that has zero credibility regarding climate science. They also completely lack transparency in regards to ownership and funding.

        Overall, we rate JunkScience.com a quackery level Pseudoscience website and a strong conspiracy website based on improbable coordination of climate scientists, globally coming to the same conclusions and for sinister purposes.

        Overall, we rate Real Climate Science a Quackery level pseudoscience website as well as a moderate conspiracy website based on promoting that the solutions for climate change lead to communism. We also rate them Low for factual reporting due to failed fact checks and a complete rejection of the consensus of science in regards to human influenced climate change.

        Overall, we rate Watts Up with That a strong pseudoscience and conspiracy website based on the promotion of consistent human influenced climate denialism propaganda.

        Overall, we rate Zero Hedge an extreme right biased conspiracy website based on the promotion of false/misleading/debunked information that routinely denigrates the left.

        Liked by 1 person

  2. Hifast · April 12, 2020

    Reblogged this on Climate Collections.

    Like

    • hunterson7 · April 13, 2020

      It is folly beyond the pale to comment on climate as an informed person but not recognize the huge machine designed to discredit and silence discussion of the issue. And this suppression is done by proponents, not skeptics.

      Like

      • Ron Clutz · April 13, 2020

        All we dissenters can hope is for the Streisand effect to take hold, provoking the curiosity of those wondering what is being censored. And of course the Al Gore effect upon the weather. And now the coronavirus effect upon Glascow COP.

        Liked by 1 person

  3. oiltranslator · April 12, 2020

    Am reading Herbal Antivirals, which convinced me I am out of my league on these topics. But I have had malaria and the sensation the fever gives is of cold and sweating, not suffocation.

    Like

    • Ron Clutz · April 12, 2020

      I have never had malaria, but here is a description of the effects:
      “After being bitten by a mosquito carrying malaria, a person will not notice symptoms for one week to one month. During this time, malaria parasites multiply in a person’s liver before invading red blood cells in the bloodstream. Once inside a person’s red blood cells, the parasites continue to multiply and spread the infection. Infected red blood cells eventually rupture, causing a person to experience flu-like symptoms that include sweating, high fevers and chills, and nausea. As the disease progresses, a person’s spleen and liver enlarge. Malaria may cause anemia or jaundice. In some severe cases, it attacks the brain and create neurological problems.”
      More at https://www.sharecare.com/health/malaria/how-malaria-affect-the-body

      Like

  4. another Jim · April 12, 2020

    How does “COVID-19 bind hemoglobin” “Here’s where COVID-19 comes in. Its glycoproteins bond to the heme,” How does the glycoprotein get into the RBC? I do not think that the Wuhan Flu directly attacks hemoglobin.
    Red blood cells do not express ACE2 on the cell surface, and so can not be infected by SARS-Cov-2. No virus in the RBC, no direct effect on hemogobin.
    https://onlinelibrary.wiley.com/doi/full/10.1002/path.1570
    It could be that SARS-CoV-2 kills enough of the ACE2 expressing cells in the lung,( kidney or other organs) to block the cleavage of angiotensin II, leading to a lung vasoconstriction crisis and hypoxia.

    Like

  5. Raymond · April 13, 2020

    Hi Ron
    I saw that video from that New York doctor trying to point out that the real nature off how the virus works very interesting. Top it off what’s really disturbing is that the hole hype around this virus has done more damage then good. I hope this is the real explanation for the viruses effect and that in the very near future the right steps will be taken to treat patients.
    Hope you’re doing just fine, I’ve been busy with other projects for clients leaving less time for climate issues. The hype around the corona virus has only made it all the more clear how easily people will panic or be panicked. The media isn’t a help here, they just add more fuel to it all. If you’re someone who wants facts to make educated decisions you’re almost considered to be a denier and someone without morals as well. Herd thinking…
    Cheers from little Switzerland

    Like

    • Ron Clutz · April 13, 2020

      Good to hear from you Raymond. I read that the Swiss are also battling this contagion and guessed you have your hands full. Perhaps you noticed the post about coronavirus infographics
      https://rclutz.wordpress.com/2020/03/20/coronavirus-infographics/
      BTW, when I went back there looking for updated images, they said they removed the daily deaths by all diseases chart because people were using it to not be alarmed.

      Like

      • Raymond · April 14, 2020

        Hi Ron
        Yea, I saw that infographic. The feedback you got doesn’t surprise me at all. What do you want to do, it’s a loosing battle to say the least. I had a discussion with someone who is with the green party here in Switzerland. Very nice person, but very naive about the science. Doesn’t know squat about CO2 but takes it at face value and thinks it’s ok. That what we are up against. People here are snitching on neighbors to the police about coronavirus infringements and on and on and on. They want to develop an app that people can use to help curb the coronavirus by informing the local authorities if there are larger gatherings in the area. This is what we have come to all over again a return to a society that want to play big brother watching you. China has done it with their own system that forces people to use a scanning system with their mobile devices that lets them move around only if they use the app. There are generation Z wants to restrict travel for everyone in the belief that this will save the environment and stop global warming. So what’s the point, you can’t talk rationally with this group of kids either … they’ve gone off the deep end. I’m glad I’m still have some sanity.

        Liked by 2 people

  6. Bob Webster · April 13, 2020

    Ron,

    Regarding mediabiasfactcheck.com, it lacks any credibility. It is a propaganda website designed to deny climate reality and blindly support climate alarmism. It has part of its name backwards (should be “biasedmediafactcheck.com”).

    Since scientific truth is never determined by consensus, their noting a website disagrees with “the scientific consensus” reveals they aren’t even staffed by credible scientists.

    The essence of The Scientific Method is skepticism… never accept a theory as if it were law; always challenge the consensus. To lack skepticism and adhere to consensus is the basis for real quackery.

    There is more scientific expertise and truth revealed by the long list of sites mediabiasfactcheck.com derides than all the IPCC summary reports put together; all of which point everyone in the opposite direction of scientific truth!

    Liked by 1 person

  7. hunterson7 · April 15, 2020

    mediabiasfactcheck is a modern Izvestia/Pravda:
    No truth in Izvestia, No news in Pravda.

    Like

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